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The lupus book : a guide for patients and their families

2024

Format:	Book
Author:	Wallace, Daniel J. (Daniel Jeffrey), 1949- author.
Title:	The lupus book : a guide for patients and their families / Daniel J. Wallace, MD, FACP, MACR, Professor of Medicine, Associate Director, Rheumatology Fellowship Program, Board of Governors, Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, California.
Edition:	Seventh edition.
Publisher, Date:	New York, NY : Oxford University Press, [2024]
Description:	viii, 336 pages : illustrations ; 24 cm illustration
Summary:	"Where should we start? The most logical place is with a definition of lupus. We look at how it is classified as a disease and place it in its proper historical perspective. This is followed by an overview of how lupus is distributed in the population-in other words, who gets the disease, which parts of the world have the highest prevalence of lupus, how many people have lupus in the United States and at what age, and which sex is most affected"-- Provided by publisher.
Subjects:	Systemic lupus erythematosus -- Popular works.
Notes:	Includes bibliographical references and index.
Contents:	Introduction and definitions -- Imflammation and immunity -- What causes Lupus? -- Where and how can the body be affected by Lupus? -- The management of Lupus Erythematosus.
LCCN:	2023054954
ISBN:	9780197689837 (hardback) 0197689833 * 9780197689851 (epub) * 9780197689868
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Library Journal Review

In this updated fifth edition, Wallace (medicine, David Geffen Sch. of Medicine, University of California, Los Angeles; The New Sjogren's Syndrome Handbook) discusses new drugs to treat lupus as well as recently discovered information about the pathology of the disease. Wallace's goal is to increase awareness and so encourage earlier diagnoses, since lupus is difficult to diagnose, and patients may have the condition for years before it is identified. The book begins with an overview and a brief history of lupus as well as its possible causes. Wallace also provides a background on inflammation and immunity as they relate to the disease. Several chapters outline the many different ways lupus can affect the body. The book includes tables and figures throughout plus a glossary of terms and a list of resources at the end. VERDICT Though the target audience is general, this book's reliance on technical jargon demands a lot from readers. Patients and their family members who seek more detail than most consumer-level books and online patient information will find this a beneficial resource.-Dana Ladd, Community Health Education Ctr., Virginia Community Univ Libs., Richmond (c) Copyright 2012. Library Journals LLC, a wholly owned subsidiary of Media Source, Inc. No redistribution permitted.

CHOICE Review

Due to the overwhelming response to his first edition (CH, May'96), Wallace (UCLA) revised and expanded his book with additional material on apoptosis, cell signaling, lupus susceptibility genes, lupus clusters, undifferentiated connective tissue diseases, selective cox-2 inhibitors, topical nonsteroidals, the use of herbs, modern immunosuppressive therapies, and osteoporosis. Relying on his vast experience with the largest lupus clinical practice in the US, Wallace writes in lay terms for the many lupus patients who lack an understanding of their disease and its potentially debilitating symptoms. The book is divided into five sections: introduction and definitions, inflammation and immunity, what causes lupus, where and how the body can be affected by lupus, and the management of lupus erythematosus. As in the first edition, the etiology of the disease, its mechanistic effects on various body organs, its most common symptoms, and its treatments are discussed so that patients and their families, including health care providers, have a current and detailed understanding. The first to write in lay language about lupus, Wallace has made a truly significant contribution, since nearly one million people suffer from the disease in the US, more than from leukemia, multiple sclerosis, cystic fibrosis, and muscular dystrophy combined. All levels. H. S. Pitkow; Temple University

Summary

Lupus, a disease of the immune system, can be quite deadly, claiming the lives of thousands of patients yearly. Dr. Daniel J. Wallace is one of the world's leading authorities on this disorder, an eminent clinician who has treated over 3,000 lupus patients, the largest such practice in America. His The Lupus Book, originally published in 1995, immediately established itself as the most readable and helpful book on the disease.Now Dr. Wallace has once again completely revised The Lupus Book, incorporating a wealth of new information. This book discusses new drug information and newly discovered information about the pathology of the disease all laid out in user-friendly language that any patient could understand. In particular, Wallace discusses the first drug for lupus to be approved by the FDA--belimumab (Benlysta)--as well as other drugs in clinical trials. Readers will also discover sections on the science of lupus and breakthroughs in research including: genetics, microbiome, and clinical trial methodology. And as in past editions, the book provides absolutely lucid answers to such questions as: What causes lupus? How and where is the body affected? Can a woman with lupus have a baby? And how can one manage this disease? Indeed, Dr. Wallace has distilled his extensive experience, providing the most up-to-date information on causes, prevention, cure, exercise, diet, and many other important topics. There is also a glossary of terms and an appendix of lupus resource materials compiled by Dr. Wallace. This new seventh edition discusses new treatments, review of pathogenesis, new laboratory tests

Table of Contents

	Preface to the Seventh Edition	vii
Part I	Introduction and Definitions
1	Why Write a Book on Lupus?	3
2	What Is Lupus?	6
3	The History of Lupus	12
4	Who Gets Lupus?	16
Part II	Inflammation and Immunity
5	The Body's Protection Plan	23
6	The Enemy Is Our Cells	35
Part III	What Causes Lupus?
7	The Genetic Connection	51
8	Environmental Villains	59
9	Drugs That May Cause Lupus or Produce Flare-Ups	67
Part IV	Where and How Can the Body Be Affected by Lupus?
10	History, Symptoms, and Signs	75
11	Must We Draw Blood?	82
12	Reactions of the Skin: Rashes and Cutaneous Lupus	87
13	Why the Aches? Arthritis, Muscles, and Bones	98
14	Pants and Pulses: The Lungs and Heart	105
15	Heady Connections: The Nervous System and Behavioral Changes	125
16	The Head, Neck, and Sjögren's Disease	144
17	What about Hormones?	151
18	The Impact of Lupus on the GI Tract and Liver	158
19	Lupus in the Kidney and Urinary Tract	170
20	The Blood and Lymphatic Systems	178
21	Why Do Blood Clots Develop?	186
22	Lupus through the Ages: Lupus in Children and the Elderly	194
23	Is It Really Lupus?	199
Part V	The Management of Lupus Erythematosus
24	How to Treat Lupus with Physical Measures	213
25	You Can Help Conquer Lupus	228
26	Taming Inflammation: Anti-Inflammatory Therapies	242
27	Big Guns and Magic Bullets: Disease-Modifying Drugs	248
28	Other Treatment Options: Treatments Occasionally Used to Manage Lupus	263
29	Fighting Infections, Vaccine Reactions, Allergies, and Osteoporosis	268
30	Can a Woman with Lupus Have a Baby?	276
31	Economic Impact of Lupus, Disability Issues, Racial and Social Disparities	285
32	What's the Prognosis?	289
33	Clinical Trials, New Therapies for Lupus, and Future Directions	296
	Glossary	305
	Appendix: Lupus Resource Materials	313
	Index	317

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